Although Peter spent his early years in San Francisco working with some of the giants of PKPD, it is for his distinguished career as a Clinical Pharmacology Leader in the Pharmaceutical Industry that he is most well-known (his industry affiliations included Napp, Beecham, Smith Kline Beecham, Pfizer and latterly GSK).
A few of his most cited publications are listed below:
Upton R., Sansom L., Guentert T., Powell R., Thiercelin J-F., Shah V., Coates P., Riegelman S. Evaluation of the absorption from 15 commercial theophylline products indicating deficiencies in currently applied bioavailability criteria, Journal of Pharmacokinetics and Biopharmaceutics (1980) 8: 229. doi:10.1007/BF01059644
M Ali, J W McDonald, J J Thiessen and P E Coates, Plasma acetylsalicylate and salicylate and platelet cyclooxygenase activity following plain and enteric-coated aspirin. Stroke. (1980) ;11:9-13 http://dx.doi.org.proxy1.athensams.net/10.1161/01.STR.11.1.9
Holford, N., Coates, P., Guentert, T., Riegelman, S. and Sheiner, L. The effect of quinidine and its metabolites on the electrocardiogram and systolic time intervals: concentration-effect relationships.. British Journal of Clinical Pharmacology, (1981), 11: 187-195. doi:10.1111/j.1365-2125.1981.tb01123.x
Ballie S., Bateman D., Coates, P.E., and Woodhouse K. Age and the Pharmacokinetics of Morphine. Age Ageing (1989) doi: 10.1093/ageing/18.4.258
Brammer, K.W. & Coates, P.E., Pharmacokinetics of fluconazole in pediatric patients, Eur. J. Clin. Microbiol. Infect. Dis. (1994) 13: 325. doi:10.1007/BF01974613
With his passing in 2006 PKUK initiated this series of lectures where each year an invited speaker could in turn be recognised for their contributions to the theory and practice of PKPD.
PKUK would like to acknowledge and thank GSK for their continued support of the Peter Coates lecture.
2022 - Colin Pillai
Clinical Pharmacology in Africa - history, progress and lessons learnt for capacity strengthening programs
2020 and 2021 - Zoom meetings - no Peter Coates Lecture
2019 - Brian Houston
Underpredicting Clearance since 1994
2018 - Jeff Aronson
How modern medicine could have saved Charles II's life
2017 - France Mentre
20 years of optimal design in pharmacometrics: what for?
2016 - Jean-Louis Steimer (Novartis)
Pharmacometrics: Aged to perfection? View of a senior citizen
2015 - Lloyd Stevens (Early Clinical)
Nothing is certain except death, taxes and ........
2014 - Mats Karlsson (Uppsala University)
A Methodological Bias
2012 - Leon Aarons (University of Manchester)
Billy Connolly's World Tour of New Zealand 2006
2011 - Lawrence Lesko (US Food and Drug Administration)
Pharmacometric Solutions: A Question-Based Review
2006 - Bob Powell (FDA)
A Reflection on Our Times and Trajectory